Gene Therapy Research Nurse inOxford inOxford PUBLISHED 7 JUN 2024

The main objective for this Gene therapy Research Nurse role is to assist in the management of the gene therapy research portfolio of the Eye Research Group Oxford department, supporting the Clinical Lead for the gene therapy programmes.
Job summary

Due to the increasing workload with the onset of new Gene Therapy (GT) trials we are looking for a Research Nurse to work alongside the existing team. We collaborate with biopharmaceutical companies, one of which focus' the development of therapies for inherited retinal dystrophies. One of the Company's lead programmes is a retinal gene therapy for Retinitis Pigmentosa (RP), a rare inherited cause of blindness that affects around 1 in 50,000 people. Gene therapy treatment has the potential to deliver a one-time treatment for RP and a range of other retinal dystrophies. Other GT trials include Wet Age-Related Macular Degeneration (AMD) and Stargardts disease.


We are looking for a dynamic Ophthalmic Research Nurse to work on various Gene Therapy related clinical trials. Working alongside an existing support team. Research experience is essential with knowledge of gene therapy & ophthalmology a bonus.


Main duties of the job

The main objective for this Gene therapy Research Nurse role is to assist in the management of the gene therapy research portfolio of the Eye Research Group Oxford department, supporting the Clinical Lead for the gene therapy programmes. Ensuring that the trials run smoothly for the participants recruited.

The post-holder will work with the gene therapy cohort of Ophthalmology patients with the Principal Investigator, and trial co-ordinator ensuring each gene therapy study is efficiently run, meeting recruitment targets.
  • Actively recruiting identified patients and running protocol related procedures relative to the role.
About us


Oxford University Hospitals NHS Foundation Trust
is one of the largest NHS teaching trusts in the country. It provides a wide range of general and specialist clinical services and is a base for medical education, training and research.

The Trust comprises four hospitals - the John Radcliffe Hospital, Churchill Hospital and Nuffield Orthopaedic Centre in Headington and the Horton General Hospital in Banbury.

Our values, standards and behaviours define the quality of clinical care we offer and the professional relationships we make with our patients, colleagues and the wider community.
We call thisDelivering Compassionate Excellenceand its focus is on our values of compassion, respect, learning, delivery, improvement and excellence.
These values put patients at the heart of what we do and underpin the quality healthcare we would like for ourselves or a member of our family. Watch how we set out to deliver compassionate excellence via theOUH YouTube channel.

Job description

Job responsibilities

The main objective for this Gene therapy Research Nurse role is to assist in the management of the gene therapy research portfolio of the Eye Research Group Oxford department, supporting the Clinical Lead for the gene therapy programmes. Ensuring that the trials run smoothly for the participants recruited.

The post-holder will work with the gene therapy cohort of Ophthalmology patients with the Principal Investigator, and trial co-ordinator ensuring each gene therapy study is efficiently run, meeting recruitment targets.
  • Liaison with the Principal Investigators, Research Co-ordinator and relevant team members to implement protocols ensuring that study specific investigations are carried out correctly and in a timely manner.
  • Be responsible and competent in the extended skills necessary to this role for example: Phlebotomy including the coordination and collection of blood samples for Biomarker and PK. Intravenous cannulation (for Flourescein Angiography / Indocyanine green), and emergency care skills as appropriate e.g management of anaphylaxis.
Job description
Job responsibilities

The main objective for this Gene therapy Research Nurse role is to assist in the management of the gene therapy research portfolio of the Eye Research Group Oxford department, supporting the Clinical Lead for the gene therapy programmes. Ensuring that the trials run smoothly for the participants recruited.

The post-holder will work with the gene therapy cohort of Ophthalmology patients with the Principal Investigator, and trial co-ordinator ensuring each gene therapy study is efficiently run, meeting recruitment targets.
  • Liaison with the Principal Investigators, Research Co-ordinator and relevant team members to implement protocols ensuring that study specific investigations are carried out correctly and in a timely manner.
  • Be responsible and competent in the extended skills necessary to this role for example: Phlebotomy including the coordination and collection of blood samples for Biomarker and PK. Intravenous cannulation (for Flourescein Angiography / Indocyanine green), and emergency care skills as appropriate e.g management of anaphylaxis.
Person Specification

professional qualifications

Essential

  • 1st level Registered Nurse with experience in Ophthalmology
Desirable

  • Experience with Gene Therapy research
Experience

Essential

  • Previous experience with Clinical trials / gene therapy.
Desirable

  • Able to demonstrate the competencies needed to develop and co-ordinate complex clinical trial protocols and regimes including complex blood programmes
Person Specification
professional qualifications

Essential

  • 1st level Registered Nurse with experience in Ophthalmology
Desirable

  • Experience with Gene Therapy research
Experience

Essential

  • Previous experience with Clinical trials / gene therapy.
Desirable

  • Able to demonstrate the competencies needed to develop and co-ordinate complex clinical trial protocols and regimes including complex blood programmes
Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the .

From 6 April 2, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. .
UK Registration

Applicants must have current UK professional registration. For further information please see

Additional information
Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the .

From 6 April 2, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. .
UK Registration

Applicants must have current UK professional registration. For further information please see

Employer details

Employer name

Oxford University Hospitals NHS Foundation Trust
Address

Oxford University Hospital NHS Trust (West Wing JR site)

Headley Way

Oxford

OX3 9DU

Employer's website
Job summary

Due to the increasing workload with the onset of new Gene Therapy (GT) trials we are looking for a Research Nurse to work alongside the existing team. We collaborate with biopharmaceutical companies, one of which focus' the development of therapies for inherited retinal dystrophies. One of the Company's lead programmes is a retinal gene therapy for Retinitis Pigmentosa (RP), a rare inherited cause of blindness that affects around 1 in 50,000 people. Gene therapy treatment has the potential to deliver a one-time treatment for RP and a range of other retinal dystrophies. Other GT trials include Wet Age-Related Macular Degeneration (AMD) and Stargardts disease.

We are looking for a dynamic Ophthalmic Research Nurse to work on various Gene Therapy related clinical trials. Working alongside an existing support team. Research experience is essential with knowledge of gene therapy & ophthalmology a bonus.


Main duties of the job

The main objective for this Gene therapy Research Nurse role is to assist in the management of the gene therapy research portfolio of the Eye Research Group Oxford department, supporting the Clinical Lead for the gene therapy programmes. Ensuring that the trials run smoothly for the participants recruited.

The post-holder will work with the gene therapy cohort of Ophthalmology patients with the Principal Investigator, and trial co-ordinator ensuring each gene therapy study is efficiently run, meeting recruitment targets.
  • Actively recruiting identified patients and running protocol related procedures relative to the role.
About us

Oxford University Hospitals NHS Foundation Trust
is one of the largest NHS teaching trusts in the country. It provides a wide range of general and specialist clinical services and is a base for medical education, training and research.

The Trust comprises four hospitals - the John Radcliffe Hospital, Churchill Hospital and Nuffield Orthopaedic Centre in Headington and the Horton General Hospital in Banbury.

Our values, standards and behaviours define the quality of clinical care we offer and the professional relationships we make with our patients, colleagues and the wider community.
We call thisDelivering Compassionate Excellenceand its focus is on our values of compassion, respect, learning, delivery, improvement and excellence.
These values put patients at the heart of what we do and underpin the quality healthcare we would like for ourselves or a member of our family. Watch how we set out to deliver compassionate excellence via theOUH YouTube channel.

Job description

Job responsibilities

The main objective for this Gene therapy Research Nurse role is to assist in the management of the gene therapy research portfolio of the Eye Research Group Oxford department, supporting the Clinical Lead for the gene therapy programmes. Ensuring that the trials run smoothly for the participants recruited.

The post-holder will work with the gene therapy cohort of Ophthalmology patients with the Principal Investigator, and trial co-ordinator ensuring each gene therapy study is efficiently run, meeting recruitment targets.
  • Liaison with the Principal Investigators, Research Co-ordinator and relevant team members to implement protocols ensuring that study specific investigations are carried out correctly and in a timely manner.
  • Be responsible and competent in the extended skills necessary to this role for example: Phlebotomy including the coordination and collection of blood samples for Biomarker and PK. Intravenous cannulation (for Flourescein Angiography / Indocyanine green), and emergency care skills as appropriate e.g management of anaphylaxis.
Job description
Job responsibilities

The main objective for this Gene therapy Research Nurse role is to assist in the management of the gene therapy research portfolio of the Eye Research Group Oxford department, supporting the Clinical Lead for the gene therapy programmes. Ensuring that the trials run smoothly for the participants recruited.

The post-holder will work with the gene therapy cohort of Ophthalmology patients with the Principal Investigator, and trial co-ordinator ensuring each gene therapy study is efficiently run, meeting recruitment targets.
  • Liaison with the Principal Investigators, Research Co-ordinator and relevant team members to implement protocols ensuring that study specific investigations are carried out correctly and in a timely manner.
  • Be responsible and competent in the extended skills necessary to this role for example: Phlebotomy including the coordination and collection of blood samples for Biomarker and PK. Intravenous cannulation (for Flourescein Angiography / Indocyanine green), and emergency care skills as appropriate e.g management of anaphylaxis.
Person Specification

professional qualifications

Essential

  • 1st level Registered Nurse with experience in Ophthalmology
Desirable

  • Experience with Gene Therapy research
Experience

Essential

  • Previous experience with Clinical trials / gene therapy.
Desirable

  • Able to demonstrate the competencies needed to develop and co-ordinate complex clinical trial protocols and regimes including complex blood programmes
Person Specification
professional qualifications

Essential

  • 1st level Registered Nurse with experience in Ophthalmology
Desirable

  • Experience with Gene Therapy research
Experience

Essential

  • Previous experience with Clinical trials / gene therapy.
Desirable

  • Able to demonstrate the competencies needed to develop and co-ordinate complex clinical trial protocols and regimes including complex blood programmes
Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the .

From 6 April 2, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. .
UK Registration

Applicants must have current UK professional registration. For further information please see

Additional information
Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the .

From 6 April 2, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. .
UK Registration

Applicants must have current UK professional registration. For further information please see

Employer details

Employer name

Oxford University Hospitals NHS Foundation Trust
Address

Oxford University Hospital NHS Trust (West Wing JR site)

Headley Way

Oxford

OX3 9DU

Employer's website


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