ARIA Clinical Research Nurse/ Clinical Research Practitioner in Cambridge inCambridge PUBLISHED WED 5 MAR 2025 Jump to job information section

ARIA is an R&D funding agency built to unlock scientific and technological breakthroughs that benefit everyone.

This post is a part-time (19 hours per week) fixed-term contract - ending 30th of September 2027. The post will be based at the Windsor Research Unit, Fulbourn Hospital, Cambridge. There will be an opportunity for flexible working in this position.

The post-holder will facilitate the journey of a research project on the ARIA portfolio from concept through to delivery. This will involve coordination with key players in the R&D departments to support ARIA Fellows navigate the design, funding, governance and PPIE requirements to move their ideas into research studies/clinical trials delivered to the study population. Where eligible, the post holder will work with the Research Fellows and Research Delivery Network to gain National Institute for Health and Care Research portfolio adoption. Once all approvals are in place, the post holder will work with the wider research delivery team to ensure successful recruitment to and delivery of these studies.An essential element of this role will involve recruitment and assessment of patients for relevant ARIA research projects according to specific trial protocols.Working in partnership with patients and families, through study specific research activities, in local and multi-centre studies, this role is central to widening opportunities to participate in groundbreaking research.

To support ARIA fellows with the development of their study protocol for submission the relevant ethics and approval committees.

To work with R&D Governance, R&D PPIE to ensure study protocols are suitable for the research objectives and deliverable in the target participant population. To work with R&D Comms lead, to ensure the study maximises its potential for successful delivery.To identify potential participants from CPFT and clinical services, other NHS trusts as relevant, community services, university and NHS databases, specialist clinics, third sector organisations, and other access routes, for ARIA portfolio studies.

Some skills include but are not limited to performing ECGs, physical examination and phlebotomy and associated processing. To perform venepuncture, process blood samples, ensure safe and appropriate storage of specimens as outlined in study protocol.To assist with other relevant investigations (including brain imaging and lumbar punctures) and process samples as required.

Maintain professional knowledge of subject area, including up to date knowledge of all relevant legislation, to ensure that all activities are carried out to the highest standard an in accordance with Trust policies, procedures and guidelines. To take an active role in the ethical requirement including research ethics submission and R&D.

About us

Please refer to the attached job description and person specification for full details of responsibilities.

1. To provide ongoing support, advice, and information to patients/volunteers with regard to their participation in clinical research in order to obtain effective informed consent. Liaise with patients, relatives, and carers on all aspects of research activity.

2. To deliver and promote ARIA and other allocated clinical trials and other research studies within the trust and externally.

3. To ensure day to day practice reflects the highest standards of governance, clinical effectiveness, safety and patient experience.

4. To work collaboratively with other colleagues to ensure all studies are delivered on time and target and are delivered in accordance with the requirements of the study protocol.

5. To safely administer all treatments and medications within the context of a clinical trial

6. To be responsible for accurate and timely completion of case report forms (CRFs). Accurate and timely completion of all study-related activities, electronically and/or in paper format.

7. To contribute to identification, management and reduction of risk.

8. To monitor treatment toxicity/side effects and ensure appropriate clinical response as required by the protocol.

9. Contribute to the development of clinical and research policies, Standard Operating Procedures.

10. To record and report adverse events that occur whilst the patient is in the clinical trial to the relevant personnel and act as required by the protocol. To immediately report, using the appropriate procedures, Serious Adverse Events (SAEs) and Suspected Unexpected Serious Adverse Reactions (SUSARs).

11. Maintain records and documentation of the studies, supporting good clinical governance, using standard databases and/or spreadsheets to regularly update Investigators, sponsors, R&D.

12. Ensure data management, quality and security according to guidelines and GCP.

13. To undertake an active role in the ethical requirements, including research ethics submission.

14. To ensure that all proposed research projects carried out in the department are registered and reviewed by the Trust R&D Department and Research Ethics Committee (REC) prior to commencement, and that updates and amendments are reported in a timely fashion.

15. To be able to critically read a research protocol, understand the methodology and its practical application within pragmatic local requirements for the studies

16. To use expert knowledge to assess appropriateness of research design and methodology and possess an understanding of the analytical process.

17. To provide advice and support to other members of the multidisciplinary team with an in-depth knowledge of ICH GCP, R&D and REC registration and approval in relation to project development, implementation, completion and dissemination.