Clinical Research Fellow in Obstetrics in Leeds inLeeds PUBLISHED THU 30 JAN 2025 Jump to job information section

Tommy's Clinical Research Fellow post in Obstetrics

Applications are invited for the Tommy's Clinical Research Fellow post at the Leeds Teaching Hospitals Trust in conjunction with the University Section of Obstetrics and Gynaecology. Clinically, the Department undertakes the full range of obstetric and gynaecological care. The post is available from January 2025.

The research areas concerns the microarchitecture of the cervix and preterm birth (Dr Orsi, Mr Simpson).

Previous research experience is desirable but not essential. It will incorporate the span of bench, clinical, and data-led studies which should appeal to a wide range of trainees with pre-existing abilities and interests.

The post is split between research (six sessions) and clinical (four sessions) as well as a full on-call rota commitment. The post also includes a commitment to undergraduate teaching and examinations as a member of the academic team. The terms and conditions of the post will be those of the NHS terms and conditions for medical and dental staff.

Please refer to attached job description and person specification.

Informal enquiries may be made by contacting Mr Nigel Simpson (tel: , email: ).

About us

JOB DETAILS

Job Title: Tommy's Clinical Research Fellow (60% research, 40% clinical).

Grade: ST4 or above

Specialty/Department: Obstetrics & Gynaecology

Site and Location: Leeds Teaching Hospitals NHS Trust Obstetrics & Gynaecology & University of Leeds

Duration of the Post: Up to 3 years (60% research, 40% clinical). Fixed term post to provide a period of training

This post was established by Leeds Teaching Hospitals Trust in conjunction with Tommy's and The University of Leeds, to encourage more senior trainees to become involved in research activity and to develop specialist interest.

Applications are now invited for a Clinical Research Fellow (Trust doctor) in Obstetrics ST4 level or above.

The specific research area relates to the microarchitecture of the cervix and its role in preterm birth.

Previous research experience is desirable but not essential. The proposed research incorporates the span of bench, clinical, and data-led studies which should appeal to a wide range of trainees with pre-existing abilities and interests.

We are seeking highly motivated, enthusiastic individuals with the potential to excel in both their clinical and research training and who have the ambition to obtain a higher degree. The post is for up to 3 years with 60% of the working week dedicated to research and 40% to clinical service. There is an on-call commitment as 2nd on call for obstetrics and gynaecology on a 1 in 10 basis. The post holder is employed by Leeds Teaching Hospital Trust (LTHT) with an honorary contract with the University of Leeds.

INFORMATION ABOUT THE DEPARTMENT

Research institution in which training will take place

The research work will be carried out in the Section of Obstetrics & Gynaecology within the School of Medicine, University of Leeds.

The Sections work covers a range of themes ranging fromunderstanding disease aetiology through to the application of our findings in translational clinical trials and currently includes the following areas of research:

Prediction/prevention of adverse pregnancy outcome - much of our work in this area aims to integrate complementary research themes so as to integrate clinical, metabolomic, proteomic, and genetic biomarkers in the pre-symptomatic detection of obstetric complications

Gynaecological cancer - we cover two principal themes; the bulk of our work revolves around the pathophysiology of endometrial cancer using genomic, transcriptomic, proteomic and lipidomic approaches. Much of our emphasis is placed on understanding the role of the tumour microenvironment in carcinogenesis. We are also interested in the role of microRNAs, predictive markers for response to novel targeted therapies, and the process of epithelial-mesenchymal transition in ovarian cancer

Interaction between nutrition and pregnancy outcome: we work closely with the Nutritional Epidemiology group in order to better understand the impact of nutrition on the incidence of pregnancy complications. Much of our research in this area has focussed on maternal caffeine and anti-oxidant intake

Endothelial biology: studying the role of mechanosensing channels in placental vasculature within the world-leading cardiovascular research group in the Leeds Institute of Cardiovascular and Metabolic Medicine

Reproductive Medicine: including pioneering in vitro maturation research and studying implantation biology

Our work is collaborative and links in with other leading national and international groups. We particularly value the practical contribution of our research in driving our teaching and clinical practice in order to improve womens healthcare.

Please refer to attached job description and person specification for full details.